The Asia Pacific region has attracted a rich array of political ecology research.  We look back over this eclectic and diverse body of work to identify three broad streams of scholarship: place-based, single issue focused research; studies of environmental narratives; and work exploring flows and networks. Much of this research focuses upon local / national / global dynamics, with relatively little attention devoted to supra-national regional processes.  In this paper we explore the potential benefits of developing a research agenda that explicitly constructs a regional political ecology.  We explore how these three themes might inform an Asia Pacific political ecology focusing on research and action on climate change mitigation and adaptation, drawing on our recent research on REDD+ and vulnerability assessment. We suggest that there are at least four possibilities that emerge from such a rescaling of political ecology. Such a project allows for: connectivities between regionally-significant actors and processes to be revealed; comparisons to be drawn that highlight similarities but also particular contextual features; challenges to the scale politics associated with climate change to better identify the agency of natures and peoples across the region; and enlivens climate activism towards more just outcomes.